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Neuroimaging of Pediatric Neuropsychiatric Disorders
Is a Picture Really Worth a Thousand Words?
Arch Gen Psychiatry. 2001;58:443-444.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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THE ARTICLE by Peterson et al1 illustrates
many pediatric neuroimaging advances of the last decade and highlights many
of the neuroimaging challenges yet to be faced. Strong features of the study
include a large sample size; careful attention to subject and control characterization,
scan acquisition, and image analysis; and recognition of the importance of
age and gender effects on brain morphometry.
A central tenet of structural imaging studies is that size matters.
Critics of the principle contend that the unimportance of size within a broad
range of extremes is demonstrated by healthy children with similar IQs having
as much as a 50% difference in brain volume,2
robust differences in brain sizes between males and females with similar functional
capacity, and the paucity of established correlations between the size of
any given brain structure and cognitive abilities. However, from a computational
science perspective it seems likely that the number of neuronal . . . [Full Text of this Article]
RELATED ARTICLE
Regional Brain and Ventricular Volumes in Tourette Syndrome
Bradley S. Peterson, Lawrence Staib, Lawrence Scahill, Heping Zhang, Carol Anderson, James F. Leckman, Donald J. Cohen, John C. Gore, John Albert, and Rebecca Webster
Arch Gen Psychiatry. 2001;58(5):427-440.
ABSTRACT
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