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In their article, Tohen et al¹ attribute to me the suggestion that the benefits of placebo have similarities with the benefits of psychotherapy; they then quote me as saying that both provide "expectation of improvement, support, and mobilization of hope."

Although I heartily endorse that suggestion, it is not mine. As I make clear in the article that they cite,² Jerome Frank made that suggestion.³ Of less concern to me, the statement "quoted" from my article,² which I also endorse, is not actually in there.

Walter A. Brown, MD
Brown Medical School
Tufts University School of Medicine
108 Driftwood Dr
Tiverton, RI 02878

1. Tohen M, Jacobs TG, Grundy SL, McElroy SL, Banov MC, Janicak PG, Sanger T, Risser R, Zhang F, Toma V, Francis J, Tollefson GD, Breier A for the Olanzapine HGGW Study Group. Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. Arch Gen Psychiatry. 2000;47:841-849. 2. Brown WA. Placebo as a treatment for depression. Neuropsychopharmacology. 1994;10:265-269. ISI | PUBMED 3. Frank JD, Frank JB. Persuasion and Healing: A Comparative Study of Psychotherapy. Baltimore, Md: The Johns Hopkins University Press; 1991.

In reply

We thank Dr Brown for pointing out that in our article,¹ we incorrectly attributed the suggestion that the benefits of placebo have similarities with the benefits of psychotherapy to Dr Brown, when it should really be attributed to Dr Frank.²

Mauricio Tohen, MD
Lilly Research . . . [Full Text of this Article]

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