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Respiration in Children at Risk for Panic Disorder
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Pine et al1 investigated the relationships
between respiratory regulation and childhood anxiety disorders. They found
that children with childhood anxiety disorders exhibited greater changes in
somatic symptoms after CO2 inhalation, and that those who developed
panic symptoms had enhanced respiratory rate increases in response to CO2 breathing, and elevated mean tidal volume levels and more variability
in respiratory rate during room-air breathing. Similar findings have been
reported in adults with panic disorder,2
supporting the idea of common pathophysiological mechanisms. However, the
question remains open as to whether respiratory dysregulation can be considered
a biological trait marker of panic spectrum disorders. We3
have found behavioral hyperreactivity to CO2 in healthy first-degree
relatives of patients with panic disorder. In their study on a comparable
study population, Coryell et al4 reported
an abnormal physiologic regulation of respiration to occur. These studies
provide initial evidence for respiration dysregulation as a trait marker for
panic . . . [Full Text of this Article]
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Response to 5% Carbon Dioxide in Children and Adolescents: Relationship to Panic Disorder in Parents and Anxiety Disorders in Subjects
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