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In addition to intrinsic, historical, and literary interest, the study of the history of a disease can have pedagogical and even clinical utility by providing memorable exemplar cases. I point out what might be the oldest known case (approximately 2600 years ago) of temporal lobe epilepsy (TLE)^1-2: the biblical figure Ezekiel, son of Buzi.³ Appreciation that Ezekiel may have had TLE might be an aid in understanding the Book of Ezekiel, which has proved largely inscrutable to previous religious, literary, and historical study.⁴

The Book of Ezekiel consists of Ezekiel's prophecies from the years 593 to 577 BC.⁴ These years include the fall of Jerusalem and the destruction of Solomon's Temple in 586. There is not much biographic information available for Ezekiel, but he is known to have come from a priestly family (Ezekiel 1:3) and thought to be a descendant of the Chief Priest Zadok.⁴ Chapters 1 to . . . [Full Text of this Article]

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