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Outcomes, Costs, and Policy Caution
A Commentary on the Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
Arch Gen Psychiatry. 2006;63:1074-1076.
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Schizophrenia is among the most serious psychiatric illnesses, causing both personal suffering and impaired functioning. Almost 90% of people with this illness are not employed, and many rely on family assistance and public support to pay for their health care and daily living expenses. In 1990, the Americans With Disabilities Act sought to increase work opportunities and reduce disability. However, between 1994 and 2003, recipients of Social Security Administration disability benefits for schizophrenia increased by 35% from 400 000 to 550 000, double the rate of increase of cardiovascular disability and 3 times the 11% growth in the adult population (Pamela Mazerski, associate commissioner, Social Security Administration, written communication, 2004).
During these years, the dissemination of second-generation antipsychotic (SGA) medications has been the most hopeful development in the medical treatment of this illness. Dozens of studies have described reduced adverse effects, better compliance, and greater symptom reduction (especially for negative symptoms and . . . [Full Text of this Article] AUTHOR INFORMATION
Robert A. Rosenheck, MD
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