This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (29)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Psychopharmacology  • Suicide  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Gen Psychiatry. 2006;63:246-248.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Suicide is the third leading cause of death in the United States at ages 10 through 24 years.¹ Major depressive disorder and depressive phases of bipolar I and II disorders are associated with most suicides. Among patients with these disorders, suicide rates are 20-times or more higher than the international general population rate of about 0.015% per year.^2-3 In addition, a lower ratio of attempted-to-completed suicide (approximately 5:1) than in the general population (approximately 25:1) suggests greater lethality of intent or methods of attempts among patients with mood disorder.^{2, 4-5}

The major public health significance of suicide and its strong association with depressive disorders encourage consideration of effects of psychiatric treatments on suicidal risk. Only clozapine has a Food and Drug Administration–approved indication for reducing risk of suicidal behavior in patients with schizophrenia, based on evidence that includes a controlled comparison with olanzapine treatment.^6-8 There is also evidence for major reduction . . . [Full Text of this Article]

AUTHOR INFORMATION
Ross J. Baldessarini, MD; Maurizio Pompili, MD; Leonardo Tondo, MD

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

RELATED ARTICLE

Suicidality in Pediatric Patients Treated With Antidepressant Drugs
Tarek A. Hammad, Thomas Laughren, and Judith Racoosin
Arch Gen Psychiatry. 2006;63(3):332-339.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Strategies for the Prevention and Treatment of Suicidal Behavior
Clayton and Auster
Focus 2008;6:15-21.
ABSTRACT | FULL TEXT  

Early Evidence on the Effects of Regulators' Suicidality Warnings on SSRI Prescriptions and Suicide in Children and Adolescents
Gibbons et al.
Am. J. Psychiatry 2007;164:1356-1363.
ABSTRACT | FULL TEXT  

Restrictions on Antidepressant Medications for Children: A Review of Medicaid Policy
Fischer et al.
Psychiatr. Serv. 2007;58:135-138.
ABSTRACT | FULL TEXT  

The Relationship Between Antidepressant Prescription Rates and Rate of Early Adolescent Suicide
Gibbons et al.
Am. J. Psychiatry 2006;163:1898-1904.
ABSTRACT | FULL TEXT  

Do Antidepressants Increase Suicidality in Younger Patients?
JWatch Psychiatry 2006;2006:1-1.
FULL TEXT