This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Schizophrenia  • Alert me on articles by topic

Ludger Tebartz van Elst, MD, PD; Dieter Ebert, MD; Bernd Hesslinger, PD, MD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Recently, Velakoulis et al¹ reported very interesting morphometric findings in a large sample of patients with different psychotic disorders. While patients with chronic schizophrenia displayed bilateral hippocampal volume reduction, patients with first-episode schizophrenia had only left hippocampal volume reduction and patients with schizophreniform disorder did not display hippocampal volume reduction at all. In contrast, patients with first-episode nonschizophrenic psychosis displayed amygdala enlargement. Velakoulis et al stress the possibility that increased amygdala volumes might be a nonspecific marker for the presence of a major affective syndrome rather than a diagnostic endophenotype of a specific nosological entity like, for example, major depression or schizophrenia. We want to support this notion and stress that amygdala enlargement has been reported in quite different neuropsychiatric entities ranging from unipolar and bipolar depression^2-3 to dysthymia in epilepsy,⁴ generalized anxiety disorder,⁵ or psychosis in . . . [Full Text of this Article]

AUTHOR INFORMATION

RELATED ARTICLE

Amygdala Volume Status Might Reflect Dominant Mode of Emotional Information Processing—Reply
Dennis Velakoulis, Stephen Wood, Michael Wong, Patrick McGorry, Alison Yung, Lisa Phillips, De Smith, Warrick Brewer, Tina Proffitt, Patricia Desmond, and Christos Pantelis
Arch Gen Psychiatry. 2007;64(2):252-253.
EXTRACT | FULL TEXT