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Chlorpromazine, Triflupromazine, and Prochlorperazine in Chronic Psychosis
THOMAS E. HANLON, Ph.D.;
KAY Y. OTA, M.S.;
CLARA LIVCHITZ, M.D.;
ALBERT A. KURLAND, M.D.
AMA Arch Gen Psychiatry 1959;1(2):223-227.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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As further phenothiazine tranquilizers become available in the treatment of the psychoses, there is an increasing need for comparative studies regarding their relative efficacy. A review of the literature indicates that such studies are now available on chlorpromazine and mepazine,1,2 promazine and mepazine,3 and promazine and chlorpromazine.4 In a previous paper by us, the effects of chlorpromazine and triflupromazine were compared in the management of the chronic, hospitalized psychotic patient.5 The following study is a continuation of the previous one, utilizing the same population and adding prochlorperazine as a final treatment phase. In this present paper the main emphasis will be on the comparative effectiveness of triflupromazine and prochlorperazine with original treatment with chlorpromazine serving as a base line. As previously, effectiveness is measured in terms of certain psychological dimensions observable in ward and interview behavior.
Procedure
The subjects originally selected
. . . [Full Text PDF of this Article]
Author Affiliations
Baltimore
Research Department, Spring Grove State Hospital.
Footnotes
Submitted for publication Oct. 3, 1958.
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