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NORMAN Q. BRILL, M.D.; EVELYN CRUMPTON, Ph.D.; SAMUEL EIDUSON, Ph.D.; HARRY M. GRAYSON, Ph.D.; LEON I. HELLMAN, Ph.D.

AMA Arch Gen Psychiatry 1959;1(3):263-272.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The purpose of this study is to investigate the covariation of certain psychiatric. psychological, physiological, and biochemical variables with improvement in psychiatric patients treated with real or simulated electroconvulsive therapy. An earlier report focused on the therapeutic effectiveness of certain components of the treatment process (i. e., electricity, convulsion, unconsciousness).³ Results indicated that the experimental variations of actual or simulated electroshock did not differ in the therapeutic effectiveness to an extent greater than chance. The present report is, therefore, concerned not with the electroshock variable but with (a) the prediction of improvement and (b) the further understanding of the concomitants of improvement.

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Author Affiliations
Los Angeles

From the Veterans Administration Center (Brentwood Neuropsychiatric Hospital), and the Department of Psychiatry and the Neuropsychiatric Institute, University of California School of Medicine.

Footnotes
Submitted for publication Oct. 7, 1958.

This study was supported in part by a grant from the Southern California Society for Mental Hygiene. Statistical analysis of data was performed on Standards Western Automatic Computer at the Institute for Numerical Analysis, U. C. L. A., under the sponsorship of the Office of Naval Research and the Office of Ordnance Research.

We acknowledge the help of W. J. Dixon, Ph.D., who acted as statistical consultant, and Ivan N. Mensh, Ph.D., who provided editorial and interpretive suggestions. The following members of the Veterans Administration Hospital staff rendered assistance in various aspects of this study: K. S. Ditman, M.D.; J. T. Ferguson, M.D.; A. S. Nissen, M.D.; R. A. Richards, M.D.; M. Schreiber, M.D.; H. D. Strassman, M.D., and A. A. Unger, M.D.

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