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Effects of Tryptophan Loading on Indole Excretion

CHARLES R. SHAW, M.D; JOHN LUCAS, Ph.D.; RALPH D. RABINOVITCH, M.D.

AMA Arch Gen Psychiatry 1959;1(4):366-371.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has been 25 years since schizophrenia was first described in children.¹ The entity of childhood schizophrenia is now well established, and there is a large literature on the subject. The relationship between the adult and the childhood form of the disease was considerably clarified by Bender’s follow-up studies^2,3 on a group of 143 schizophrenic children; she found that 89% of these children were considered by independent observers to have schizophrenia when examined in adulthood. Further clarification of this relationship occurs in the similarity between what has been called the core pathology of childhood schizophrenia, i. e., dysidentity,⁴ and Federn’s description⁵ of the fundamental psychopathology of adult schizophrenia as an ego defect, with loss of ego boundaries and a failure to differentiate the self from the external world.

Federn believes that the ego is more than a concept, that the familiar experience of . . . [Full Text PDF of this Article]

Author Affiliations
Northville, Mich.

Footnotes
Submitted for publication Jan. 20, 1959.

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