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I. Turner's Syndrome

DUANE ALEXANDER, BS; H. T. WALKER, JR.; JOHN MONEY, PhD

Arch Gen Psychiatry. 1964;10(4):337-339.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Abnormalities of psychologic functioning in patients with Turner's syndrome are of interest owing to their possible relationship to the well-documented cytogenetic origin of the condition.

Turner's syndrome, also known as gonadal aplasia, ovarian agenesis, and gonadal dysgenesis, was first described by Turner in 1938 and has since then been extensively studied and characterized, for example by Haddad and Wilkins, 1959, and Wilkins, 1957. The genetic defect in 80% of the cases is one in which the sex chromatin is negative and the chromosome count 45, XO, instead of the normal 46,XX. Other cases have been shown to be chromatin positive and to have XO/XX, XO/XXX, or other mosaicisms, or to have chromosome deletions or translocations.

Shaffer in 1962 first called attention to a peculiar psychologic abnormality in Turner's syndrome that was associated with a Wechsler Performance IQ significantly lower than Verbal IQ. Applying Cohen's . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

Associate Professor of Medical Psychology and Pediatrics (Dr. Money), The Johns Hopkins University, Department of Psychiatry.

Footnotes
Submitted for publication Nov 14, 1963.

The research for this paper was supported by grants No. M-1557, MH-K3-18,635, and 2M-5913, National Institutes of Health, United States Public Health Service.

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