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ARNOLD J. MANDELL, MD; IRENE MERSOL-SABBOT, MS; MARY P. MANDELL, MS

Arch Gen Psychiatry. 1964;10(5):513-518.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Recent reports by Hill et al,¹ Thorn,² and others on the subject of "idiopathic pedal edema" in psychologically disturbed females has generated some interest in the study of psychological factors in the production of water retention states in general. Though this syndrome appears to be a distinct entity and apparently unrelated to demonstrable cardiac, renal, or hepatic disease, one may speculate that it may be reflective of an exaggeration of a normal phenomenon: the retention of water during a psychologically disturbed state. Recent psychosomatic research, documented in the areas of functional hypoglycemia and hypersecreting ulcer patients in relationship to uropepsin levels,³ indicates that many of the so-called psychosomatic disease entities are probably exaggerations of normal physiological events. Thus, the possibility that psychological state may significantly influence water balance may have implications for refractory edematous states of various primary etiologies, the . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

Biochemical Correlates Laboratory, Department of Psychiatry, UCLA Center for the Health Sciences.

Footnotes
Submitted for publication Dec 31, 1963.

Supported by grant No. 61-2-22 from the State of California Department of Mental Hygiene.

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