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  Vol. 11 No. 1, July 1964 TABLE OF CONTENTS
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Interaction of Multiple Determinants of Schizophrenia

A Tentative Synthesis and Review

W. J. FESSEL

Arch Gen Psychiatry. 1964;11(1):1-18.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

That other world, whose relationship to the ordinary one is the relationship of the wilderness to the cultivated land.

—Kafka

Disease is the common result of a variety of diverse external and internal causes.

—Pidoux

The main purposes of this paper are to consider some of the determining factors of schizophrenia; to suggest a paradigm for their interaction which accounts for both the temporal sequence and energy relationship of the involved events; to show the advantage of regarding schizophrenia as a disturbance of the whole organism in which there is a generalized physiological dysfunction, rather than as a dysfunction of the brain alone; and to demonstrate that the so-called psychodynamic and organic schools of pathogenesis are not so irreconcilable as some suppose.

It is emphasized at the outset that many questions raised in this paper probably cannot be answered by direct experiment. . . . [Full Text PDF of this Article]


Author Affiliations

MRCP (Lond, Edin) SAN FRANCISCO


Footnotes

Submitted for publication Feb 4, 1964.

Assistant Clinical Professor of Psychiatry and Medicine, University of California School of Medicine.

Supported in part by PHS grants MH 04581-03 and MH 07536-01 from The National Institute of Mental Health, and in part by grant 61-1-29 from The California Department of Mental Hygiene.



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