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A Pilot Study

EDWARD J. KOLLAR, MD; GRANT R. SLATER, PhD; JAMES O. PALMER, PhD; RICHARD F. DOCTER, PhD; ARNOLD J. MANDELL, MD

Arch Gen Psychiatry. 1964;11(2):113-125.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

This is a study of psychological, physiological, and biochemical variables associated with starvation. Although laboratory experiments on rats^27-30 indicate that these animals respond to acute starvation with adrenalcortical activation, there is reason to question whether this occurs in humans and other animals. Keys¹⁰ reports that starving man has a low metabolic rate, bradycardia, hypotension, hypothermia, and great muscular weakness. A starving man typically states he is depressed and his facies suggest depression more than emaciation. He becomes increasingly quiet, somber, apathetic, and slow in motion. Although he reports increasing irritability, there is little overt indication of it. The starving man conserves energy in every possible way. Severe neurotic symptoms developed in the Minnesota Experiment¹¹ in which 35 "normal" young men were starved. There was a full return to normal on nutritional rehabilitation. In the Minnesota Experiment neither . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

Department of Psychiatry and The Neuropsychiatric Institute, Center for the Health Sciences, University of California, and Department of Neurobiochemistry, Veterans Administration Center.

Footnotes
Submitted for publication Jan 24, 1964.

This investigation was supported by research grants No. 60-2-18 and No. 61-2-22 from the California Department of Mental Hygiene, and research grant NB03556 from the National Institute of Health.

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