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III. Delay or Prevention of Hospitalization

DAVID M. ENGELHARDT, MD; NORBERT FREEDMAN, PhD; BERNARD ROSEN, BA; DAVID MANN, PhD; REUBEN MARGOLIS, PhD

Arch Gen Psychiatry. 1964;11(2):162-169.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This paper is the third in a series of investigations into the factors influencing hospitalization of schizophrenic outpatients. In a previous publication it was shown that chlorpromazine had a marked effect in reducing the incidence of hospitalization among ambulatory chronic schizophrenics.¹ Further exploration revealed that although chlorpromazine was most effective early in treatment, its effectiveness diminished progressively over time.² In contrast, the hospitalization rates for placebo treated patients were similar regardless of length of treatment exposure. The data presented in the latter publication indicate that duration of treatment exposure is an important variable to be considered when evaluating the effectiveness of drug treatment in influencing the incidence of hospitalization among chronic schizophrenic outpatients.²

The suggestion that length of treatment exposure plays an important role in determining the results obtained with phenothiazine treatment has many implications. The . . . [Full Text PDF of this Article]

Author Affiliations
BROOKLYN, NY

Professor, Executive Officer, Department of Psychiatry (Dr. Engelhardt), Associate Professor, Department of Psychiatry (Dr. Freedman), Junior Research Psychologist, Department of Psychiatry (B. Rosen), Assistant Professor, Department of Psychiatry (Dr. Mann), Instructor, Department of Psychiatry, Downstate Medical Center (Dr. Margolis).

Footnotes
Submitted for publication Jan 27, 1964.

This study was supported in part by a grant from the National Institute of Mental Health, United States Public Health Service.

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