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Apparent Eye Level TestIts Background and Use in Psychopoharmacology
DONALD M KRUS, PhD;
OSCAR RESNICK, PhD;
MILTON RASKIN, MD
Arch Gen Psychiatry. 1966;14(4):419-427.
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THE INTRODUCTION of drugs as part of the therapeutic armamentarium in psychiatry has fostered, in recent years, ever burgeoning research activity concerned with elucidating the central mechanism of action of psychoactive drugs. A significant part of this activity involves attempts to correlate the behavioral action of psychoactive drugs with biochemical changes in man. Since no practical way exists for directly assessing the action of such drugs on brain chemistry in man, biochemical changes, by necessity, have been followed peripherally in the blood and urine. The lack of direct methods has led researchers to rely heavily on animal data to form the basis for postulating the mechanisms of action of psychoactive drugs in man. When one studies these data, however, it becomes apparent that psychoactive drugs have different chemical, pharmacologie, and behavioral effects in different species or classes of animals (see for example, Resnick1). Thus, although the animal data have been the
. . . [Full Text PDF of this Article]
Author Affiliations
WORCESTERM, MASS; SHREWSBURY, MASS; NORWICH, CONN
From the Department of Psychology and Heinz Werner Institute of Developmental Psychology, Clark University, Worcester, Mass (Dr. Krus); Worcester Foundation for Experimental Biology, Shrewsbury, Mass (Dr. Resnick); and Abraham Rihicoff Research Center, Norwich Hospital, Norwich, Conn (Dr. Raskin).
Footnotes
Submitted for publication June 21, 1965.
Reprint requests to Clark University, Department of Psychology, Worcester, Mass 01610 (Dr. Krus).
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