This Article  • References  • Full text PDF  • Correction  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (23)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

E. RODIN, MD; E. LUBY, MD

Arch Gen Psychiatry. 1966;14(4):435-441.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE the accidental discovery of the Psychosomimetic properties of Lysergic acid diethylamide (LSD-25) by Stoll,¹ in 1947, a great amount of work has been carried out to elucidate the behavioral effects and pathophysiological mechanisms of action of this substance. The literature on this topic is steadily growing and contains now more than 1,000 publications.²

There are several studies available that report on the electroencephalographic changes resulting from LSD administration to humans as seen by surface recordings^3-9 and there are also some observations on changes in the human depth electrogram.^10-13 It is generally agreed that the amplitude of the EEG decreases, -rhythms tend to disappear and the tracings become of the lowvoltage fast or desynchronized type. Gastaut⁴ reported that the average -frequencies are increased by 0.5 to 4 cycles per second (cps) and Grey Walter⁷ noted an increase from 11.6 to . . . [Full Text PDF of this Article]

Author Affiliations
DETROIT

From Lafayette Clinic, Michigan Epilepsy Center, Wayne State University, Detroit.

Footnotes
Submitted for publication Sept 24, 1965.

Reprint requests to Lafayette Clinic, Michigan Epilepsy Center, Wayne State University, Detroit 48207 (Dr. Rodin).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?