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During and After Phenothiazine Therapy

GEORGE HENINGER, MD; LOUISE B. SPECK, PhD

Arch Gen Psychiatry. 1966;15(4):419-426.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

MEASUREMENT of the sensory evoked cerebral response in man has been greatly facilitated by the advent of electronic techniques for averaging out the background activity.¹ This development has fostered increased interest in the possibility of finding physiological correlates of psychologic phenomena in both healthy and mentally ill populations. In normal subjects, sensory evoked response characteristics have been found to vary with changes in perception, attention, stimulus uncertainty, and extroversion.^2-11 There are also differences relating to sex and age.¹¹ Psychiatric patients have been shown to differ from nonpatients in the reactivity cycle and in the intensity response gradient of the somatosensory evoked response.^12-15 In psychotic depressed patients, the reactivity cycle was found to improve as their clinical condition improved.¹³ Similarly, abnormalities in the auditory evoked response in schizophrenics were found to change toward normal as their clinical state improved. . . . [Full Text PDF of this Article]

Author Affiliations
BETHESDA, MD, AND WASHINGTON, DC

From the National Clearing House for Mental Health Information (Dr. Heninger) and the Clinical Neuropharmacology Research Center, National Institute of Mental Health, National Institutes of Health, Bethesda, Md, and St. Elizabeth's Hospital, Washington, DC (Dr. Speck). Dr. Heninger's present address is the Connecticut Mental Health Center, New Haven.

Footnotes
Submitted for publication May 13, 1966.

Reprint requests to William A. White Bldg, Room 508, St. Elizabeth's Hospital, Washington, DC 20032 (Dr. Speck).

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