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IV. Delay or Prevention of Hospitalization—A Reevaluation*

DAVID M. ENGELHARDT, MD; BERNARD ROSEN, MA; NORBERT FREEDMAN, PhD; REUBEN MARGOLIS, PhD

Arch Gen Psychiatry. 1967;16(1):98-101.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THIS PAPER is the fourth in a series of investigations into the factors influencing hospitalization of schizophrenic outpatients. In the first publication it was shown that chlorpromazine had a marked effect in reducing the incidence of hospitalization among ambulatory chronic schizophrenic Patients.¹ Further exploration revealed that although chlorpromazine was highly effective early in treatment, its effectiveness diminished progressively over time, suggesting delay rather than prevention of hospitalization. In contrast to phenothiazine-treated patients, the hospitalization rates for groups of patients treated with placebo were similar, regardless of duration of treatment exposure.² A review of the literature found a similar consistency in the hospitalization rates reported for placebo-treated patients (25% to 30%),² suggesting the existence of a finite subgroup of "hospitalization prone" patients in any given group of ambulatory schizophrenic patients. In addition, the consistency in the hospitalization rates of placebo-treated groups suggests . . . [Full Text PDF of this Article]

Author Affiliations
BROOKLYN, NY

From the Psychopharmacology Research Unit, Department of Psychiatry, State University of New York, Downstate Medical Center, Brooklyn.

Footnotes
Submitted for publication May 25, 1966.

Reprint requests to 450 Clarkson Ave, Brooklyn, NY 11203 (Dr. Engelhardt).

Parts I and II of this series were published in the Journal of the American Medical Association^1,2 and Part III in the ARCHIVES OF GENERAL PSYCHIATRY.³

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