This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (506)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Its Effect Against Recurrent Depressions and Manic-Depressive Psychosis

Poul Christian Baastrup, MD; Schou Mogens, MD

Arch Gen Psychiatry. 1967;16(2):162-172.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE SPECIFIC therapeutic effect of lithium in manic phases of the manicdepressive psychosis was first observed in 1949¹ and was confirmed later in controlled studies,^2,3 as well as in a number of uncontrolled ones. A prophylactic action of the drug against both the manic and depressive phases of the illness could be noted in a few of the patients described by Schou et al.² More systematic and detailed observations of this effect were made independently by Hartigan⁴ and Baastrup,⁵ and the term normothymotics was proposed for drugs with a specific action against manic-depressive psychosis.⁶

In order to demonstrate prophylactic drug action in a disorder such as manicdepressive psychosis, which is characterized by a capricious and largely unpredictable course, one must study a large number of patients who have a sufficiently high risk of relapse and who are observed for . . . [Full Text PDF of this Article]

Author Affiliations
Glostrup, Risskov, Denmark

From the Psychiatric Hospital, Glostrup (Dr. Baastrup); and the Psychopharmacology Research Unit, Institute of Psychiatry, Risskov, and Aarhus University School of Medicine (Dr. Schou).

Footnotes
Submitted for publication July 8, 1966.

Reprint requests to the Psychopharmacology Research Unit, Institute of Psychiatry, Risskov, Denmark (Dr. Schou).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?