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Corticosteroid Responses to Psychotherapy of DepressionsI. Evaluations During Confrontation of Loss
Edward J. Sachar, MD;
John M. Mackenzie, MD;
William A. Binstock, MD;
John E. Mack, MD
Arch Gen Psychiatry. 1967;16(4):461-470.
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THIS PAPER will report psychological and endocrinological observations on six hospitalized female patients receiving Psychotherapy for depressive reactions.
The study was designed to test endocrinologically a familiar psychiatric formulation first proposed by Freud in 1917:1 one type of depressive reaction is regarded as precipitated by a loss, defined as a loss of a loved object or ideal. The patient responds initially with affective distress, and then goes on to form a pathological symptom syndrome in which, for example, self-recrimination may be a prominent feature, but in which the painful loss is not affectively acknowledged. Many of the depressive symptoms which the patient forms may be regarded as serving, in part, defensive or restitutive functions, in that these symptoms operate to help the patient avoid experiencing the painful loss. It is this type of depressive reaction which was well described by Freud, Abraham,
. . . [Full Text PDF of this Article]
Author Affiliations
Boston
From the Psychoendocrine Research Laboratory and the Center for Clinical and Metabolic Studies of Affective Disorders, Massachusetts Mental Health Center, and the Department of Psychiatry, Harvard Medical School, Boston.
Footnotes
Submitted for publication Sept 23, 1966.
Read in part before the annual meeting of the American Psychosomatic Society, Chicago, March 18, 1966.
Reprint requests to Montefiore Hospital and Medical Center, 111 E 210th St, Bronx, NY 10467 (Dr. Sachar).
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