This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (17)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Robert L. McDonald, MD

Arch Gen Psychiatry. 1967;17(6):680-686.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PARADOXICAL effects coincident with drug administration have been observed clinically for some years. The advent of psychochemotherapeutic agents during the last decade or so has resulted in a noticeable increase in the incidence of these reactions. Although these reactions have by no means been confined to any generic class, the most marked paradoxical responses have been reported in relation to phenothiazine usage where, not infrequently, patients become markedly more agitated and anxious, rather than calmer and less anxious as would be expected from the pharmacological properties of phenothiazines. An early observer of these reactions, Sarwer-Foner,^1-3 hypothesized that "the typical pharmacological effect (of the tranquilizing drug) chemically removes or interferes with activities used by the patient as major defenses against unconscious underlying conflicts." Stated more specifically, persons who characteristically are outgoing and physically interactive with their environment will respond with . . . [Full Text PDF of this Article]

Author Affiliations
Atlanta

From the Department of Management, Georgia State College, Atlanta.

Footnotes
Submitted for publication June 26, 1967.

Reprint requests to 33 Gilmer St, Atlanta, 30309.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?