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E. K. KORANYI, M.D.; H. E. LEHMANN, M.D.

AMA Arch Gen Psychiatry 1960;2(5):534-544.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In this investigation the effects of 100 consecutive hours of wakefulness were studied in six chronic psychotic hospital patients. It was intended to observe, record, and measure physiological and psychological changes occurring during prolonged wakefulness and to study the possible influence of this specific stress on the course of the psychotic process. Although there are many references to experimental sleep deprivation in animals and in healthy volunteers, we could not find reports on similar experiments in psychotic subjects in the literature.

Previous Observations

Patrick and Gilbert¹ investigated the effects of sleep deprivation in 1896. Three subjects were kept awake for 90 hours. The authors observed a tendency to visual hallucinations in one subject. Later, Robinson and Hermann,² Laslett,³ and others reported on several investigations of sleep deprivation in humans and in animals.

The sleep deprivation ranged from 60 to more . . . [Full Text PDF of this Article]

Author Affiliations
Montreal

From the Verdun Protestant Hospital and the Department of Psychiatry, McGill University Faculty of Medicine.

Footnotes
Submitted for publication Dec. 7, 1959.

We wish to express our appreciation for the cooperation of Dr. George E. Reed, former Medical Superintendent of the Verdun Protestant Hospital, and we are particularly indebted to members of the hospital staff who aided in performing this experiment. Thanks are also due to Dr. Gerald J. Sarwer Foner for his valuable assistance in reviewing this report. Above all, we wish to express our gratitude to our six patients, whose cooperation made this experiment possible.

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