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D. F. Caldwell, PhD; A. J. Brane, MD; P. G. S. Beckett, MD

Arch Gen Psychiatry. 1970;22(6):500-503.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

RECENT evidence suggests a relationship in humans between reduction of stage-4 sleep (viz, high voltage, slow waves) and varying degrees of thought disturbance. Notable are the reports of marked decrease in stage-4 patterning in chronic schizophrenic patients^1-6 and patients with depression and manic-depressive illness, depressed phase.^7-10 Moreover, Feinberg and Carlson¹¹ observed stage-4 sleep to be a hyperbolic function of age, with verbal performance IQ a parabolic function showing maximum decline at periods of minimum stage-4 sleep. Hallucinations accompanying the symptoms of acute alcohol withdrawal were found to be inversely related to amount of stage-4 sleep.¹²

The present investigation studied the allnight sleep electroencephalograms and power-density configurations for a group of psychotic and normal prepuberal children. Particular attention was focused on whether stage-4 sleep was affected in the psychotic population who were clearly manifesting thought disorders.

Methods

Subjects.—This study included 12 boys and seven . . . [Full Text PDF of this Article]

Author Affiliations
Detroit

From the Division of Psychobiology and Division of Psychiatry, Lafayette Clinic, Detroit. Dr. Beckett is presently at the Department of Psychiatry, Trinity College, Dublin, Ireland.

Footnotes
Submitted for publication Oct 8, 1969.

Read before the Midwestern Psychological Association, Chicago, May 2, 1968.

Reprint requests to Division of Psychobiology, Lafayette Clinic, 951 E Lafayette, Detroit 48207 (Dr. Caldwell).

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