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Frederick T. Melges, MD; Jared R. Tinklenberg, MD; Leo E. Hollister, MD; Hamp K. Gillespie

Arch Gen Psychiatry. 1970;23(3):204-210.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WE HAVE recently reported that marihuana extract, calibrated for content of (—)-¹-tetrahydrocannabinol (THC), significantly impaired the serial coordination of cognitive operations during a task that required sequential adjustments in reaching a goal.¹ Our term for this mental incoordination is temporal disintegration. From a cognitive standpoint, temporal disintegration means that the individual has difficulty in retaining, coordinating, and serially indexing those memories, perceptions, and expectations that are relevant to the goal he is pursuing. Subjectively, temporal disintegration is experienced as a confusion of past, present, and future while a person attempts to pursue goals. This paper focuses on the relationship of temporal disintegration to depersonalization (that is, the experience of the self as strange and unreal) during marihuana intoxication.

Hypotheses

Since the personal past, present, and future constitute a fundamental subjective framework through which an individual views and identifies himself, we postulated that the fragmentation and disorganization of temporal experience . . . [Full Text PDF of this Article]

Author Affiliations
Stanford, Calif

From the departments of psychiatry (Drs. Melges and Tinklenberg) and medicine (Dr. Hollister), Stanford University School of Medicine, Stanford Calif, and the Veterans Administration Hospital, Palo Alto, Calif (Dr. Hollister and Mr. Gillespie).

Footnotes
Accepted for publication June 25, 1970.

Reprint requests to Department of Psychiatry, Stanford University School of Medicine, Stanford, Calif 94305 (Dr. Melges).

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