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Disparities in the Prevalence of Abnormalities

Daniel J. Luchins, MD

Arch Gen Psychiatry. 1982;39(7):859-860.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1976, Johnstone et al¹ reported the first computed tomography (CT) study in schizophrenia. They observed enlarged lateral ventricles in more than 50% of their sample of middle-aged patients undergoing longterm hospitalization. Three years later, Weinberger et al² studied a larger and younger population of research patients at the National Institute of Mental Health (NIMH), and they noted enlarged ventricles (2 SDs greater than normal) in a similar proportion. This group also reported enlarged cortical sulci³ and an increased frequency of reversed cerebral asymmetry.⁴ Subsequent studies have reported striking differences in the prevalence of ventricular enlargement in schizophrenia. For example, Golden et al⁵ noted enlarged ventricles in 60% of their sample, while Andreasen et al^* noted it in only 6%. In this issue of the ARCHIVES, along with two reports of enlarged ventricles in schizophrenics by Nasrallah et al and Weinberger et al (see pp . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Psychiatry, University of Chicago.

Footnotes
Accepted for publication May 3, 1982.

Reprint requests to Department of Psychiatry, Box 411, University of Chicago, 950 E 59th St, Chicago, IL 60637 (Dr Luchins).

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