Hat Size in Schizophrenia-Reply
Nancy C. Andreasen, MD, PhD
Department of Psychiatry
James C. Ehrhardt, PhD
Department of Radiology
Judith H. W. Crossett, MD
Department of Psychiatry University of Iowa Hospitals and Clinics Iowa City, IA 52242
Henry A. Nasrallah, MD;
Jeffrey A. Coffman, MD;
Stephen C. Olson, MD
Department of Psychiatry Ohio State University School of Medicine 473 W 12th Ave Columbus, OH 43210
William M. Grove, PhD
Department of Psychiatry University of Minnesota Box 393 Mayo Mayo Memorial Building Minneapolis, MN 55455
Val Dunn, MD
Department of Radiology American Fork Hospital 170 North 1100 East American Fork, UT 84003
Arch Gen Psychiatry. 1987;44(7):674-676.
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To the Editor.—
When we initially obtained the results concerning cranial, cerebral, and frontal lobe size that were reported in the February 1986 issue of the ARCHIVES, we were puzzled and even slightly embarrassed by the cranial measures. The criticisms suggested in the preceding letters also occurred to us: MRI is a costly and cumbersome way to measure cranial size (although it is almost never traumatic), and the implication that something as simple as head size might have pathologic meaning seems unduly simple-minded. We examined all sources of artifact that we could think of (eg, height and weight), and concluded that these did not explain the findings. We then had two choices: to report the findings so that others could attempt to replicate them (since they were potentially of important pathologic significance), or to report only the frontal and cerebral findings. After some thought, we concluded that we were scientifically obligated to
. . . [Full Text PDF of this Article]
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