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Diagnosing DiagnosesReceiver Operating Characteristic Methods and Psychiatry
John K. Hsiao, MD;
John J. Bartko, PhD;
William Z. Potter, MD, PhD
Arch Gen Psychiatry. 1989;46(7):664-667.
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With every issue of the ARCHIVES, the reader is inundated with psychiatric research: new treatments, new biological abnormalities, new diagnostic methods, new diagnoses—the list seems endless. It is difficult to conceive of anyone, except, of course, our dedicated Editor, who bothers to read every article in every issue. Indeed, it would be a rare individual who had the time to read every abstract. In the current issue of the ARCHIVES, Mossman and Somoza1 reexamine the dexamethasone suppression test (DST) using a statistical method that is new to psychiatry, namely, receiver operating characteristic (ROC). Using this method, they are able to demonstrate that there is significant variability in the performance of the DST among different psychiatric centers. As with any statistical method, ROC involves more than a little mathematics, and the natural question as one leafs through the See also p 653. ARCHIVES is "Why should I bother with this?"
. . . [Full Text PDF of this Article]
Author Affiliations
From the Section on Clinical Pharmacology, Laboratory of Clinical Science (Drs Hsiao and Potter), and the Division of Biometry and Applied Sciences (Dr Bartko), National Institute of Mental Health, Bethesda, Md.
Footnotes
Accepted for publication Sept 23, 1988.
Reprint requests to the Section on Clinical Pharmacology, Laboratory of Clinical Science, National Institute of Mental Health, Bldg 10, Room 2D46, Bethesda, MD 20892 (Dr Hsiao).
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