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BERNHARD BOGERTS, MD; Peter Falkai, MD; Benno Greve, MD
Department of Psychiatry University of Düsseldorf Postfach 12 05 10 W-4000 Düsseldorf 12 West Germany

Arch Gen Psychiatry. 1991;48(10):956-957.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

In the postmortem brain material of the Würzburg collection, Heckers et al¹ found only a subtle trend toward volume reduction of the total left hippocampal formation in schizophrenic patients (-6%, P =.187). There were no significant volume changes in the right hippocampus or the right and left amygdala. In the same collection, no differences in the volumes of the parahippocampal gyrus were found.² The authors believe the discrepancy with our previous findings of reduced hippocampal, amygdala, and parahippocampal gyrus volumes in schizophrenic persons are a result of methodologic shortcomings in our 1985 article.³ However, the results obtained from the material of the Würzburg collection^1,2 are not only in contrast with our 1985 findings, they also refute six other postmortem studies^4-9 that gave planimetric evidence of reduced parahippocampal gyrus^4,6,7 or hippocampal^5,8,9 size in schizophrenic patients. Moreover, according to the declared . . . [Full Text PDF of this Article]

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