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II. Physiological Differentiation of Reactive and Endogenous Depression

BERNARD L. BUSFIELD, JR., M.D.; HENRY WECHSLER, Ph.D.; WILLIAM J. BARNUM, M.D.

Arch Gen Psychiatry. 1961;5(5):472-477.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has been pointed out elsewhere¹ that objective clinical study of both psychological and somatic manifestations of mental illness are necessary to delineate diseases as they occur in nature and not as they are necessarily classified by man. In the psychophysiological states known as depression, psychic and somatic disturbances are more complicated than the psychomotor retardation frequently assumed.² Though direct observation of physiological changes in depressed states has been reported, psychopathology of depression has received much more emphasis and study.

Renewed interest in specific physiological changes associated with depression has occurred with the reexploration of disturbances of salivation in depressed patients. Twenty years ago the pioneering work of Strongin and Hinsie³ and Winsor^4,5 focused on the collection of saliva from the parotid gland using the Lashley suction cup technique. It was shown that patients with depression salivate . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

Massachusetts Mental Health Center and Department of Psychiatry, Harvard Medical School.

Footnotes
Submitted for publication June 2, 1961.

A number of the findings reported in this paper were presented at the Third World Congress of Psychiatry in Montreal, June, 1961.

The study reported in this paper was conducted under the auspices of the Anti-Depressant Drug Project under a research grant from the Psychopharmacology Service Center, National Institute of Mental Health, Public Health Service. The authors are grateful to Milton Greenblatt, M.D., and George H. Grosser, Ph.D., for their help in the study.

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