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Rachel G. Klein, PhD
Columbia University College of Physicians and Surgeons 722 W 168th St New York, NY 10032

Paul Wender, MD
Salt Lake City, Utah

Arch Gen Psychiatry. 1995;52(6):429-433.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SOME OF the articles appearing in this issue of the ARCHIVES document the current interest in the varied applications of methylphenidate hydrochloride in psychiatry. Together, the articles address questions that have been of concern to clinicians and scientists alike. The scope of the clinical use of methylphenidate in adult psychiatry is addressed in the study by Spencer and associates¹; a potentially serious side effect (ie, tics) is examined carefully by Gadow et al²; and Volkow and colleagues³ report on some mechanisms of methylphenidate activity and their contribution to our understanding of the drug's effects.

In an excellent review that appeared in the ARCHIVES in 1987, Chiarello and Cole⁴ summarize the manifold uses of methylphenidate, as well as those of other psychostimulants. Although the literature consisted mostly of less than

See also pages 434, 444, 456, and 464

well-controlled studies conducted in imprecisely identified patient groups, the conclusions pointed to the likely usefulness of psychostimulants . . . [Full Text PDF of this Article]

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