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E. GELLER, Ph.D.; N. Q. BRILL, M.D.; E. CRUMPTON, Ph.D.; S. EIDUSON, Ph.D.; E. LISTON; L. MIZRAHI

Arch Gen Psychiatry. 1962;6(5):384-387.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Reports indicating that schizophrenic patients exhibited increased adrenocortical activity,¹ decreased activity,² or normal activity³ may be found in the literature. In an earlier report⁴ from this laboratory an attempt was made to resolve this controversy. A study of 96 hospitalized psychotic patients revealed no significant difference from normals in the various reflectors of adrenocortical activity measured. However, in the course of the study, a significant correlation between those various measures of adrenocortical activity and severity of illness as measured by psychological and psychiatric parameters^* was obtained. These findings suggested that one source of error leading to the conflicting reports may have been different levels of severity of illness in the patient groups selected.

The purpose of the experiment reported here was, therefore, to test the hypothesis that more severely ill patients demonstrate lower adrenocortical activity than less severely . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

The Department of Psychiatry and The Neuropsychiatric Institute, UCLA Medical Center.

Footnotes
Submitted for publication Oct. 31, 1961.

This study was supported in part by U.S. Public Health Service Summer Fellowship Grants to the UCLA Department of Psychiatry.

Clinical Evaluation, Lorr Deviation, Lorr Schizophrenic Scale, Bizarreness, Most Pathological Breakdown of Ego Function, Frequency of Breakdown of Ego Function. See Ref. 5 for a more complete description of the parameters.

Disorganization Level Inventory is a questionnaire developed at the Neuropsychiatric Hospital, VA Center, Los Angeles, and the Department of Psychiatry, UCLA Medical Center. It consists of a series of questions to be answered by ward personnel covering the social behavior of the patient.

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