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The "Antibrain" Factors in Psychiatric Patients' SeraI. Further Studies With a Hemagglutination Technique
W. J. FESSEL
Arch Gen Psychiatry. 1963;8(6):614-621.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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In preliminary reports1,8 it was shown that sera of some psychiatric patients had a greater effect than did control sera upon latex particles coated with brain extracts. Because in further experience with the latex particle system there were difficulties in reproducing the results, a red cell agglutination reaction that is both easier to read and more reproducible has been developed. The results obtained with this system confirm the original findings in a general way, but also cast doubt upon the interpretation, mentioned in the previous report as possible, of a circulating brain antibody in the sera of mentally ill patients.
Materials and Methods
A. Patient Material.—Psychiatric patients' sera were obtained from several institutions of the California Department of Mental Hygiene, the majority coming either from the patients with acute mental disturbances on the acute treatment service of the Langley Porter Neuropsychiatric Institute or from
. . . [Full Text PDF of this Article]
Author Affiliations
MRCP (Lond & Edin) SAN FRANCISCO
The Departments of Psychiatry and Medicine, University of California School of Medicine, and the Langley Porter Neuropsychiatric Institute, California Department of Mental Hygiene.
Footnotes
Submitted for publication Dec 24, 1962.
Supported by a grant (MY4581) from the National Institutes of Health.
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