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Abstract 1 of 1
Arch Gen Psychiatry. 2002;59:225-231.
Background This study used longitudinal data to examine the extent to which young
people with depression in mid adolescence (ages 14-16) were at increased risk
of adverse psychosocial outcomes in later adolescence and young adulthood
(ages 16-21).
Methods Data were gathered during a 21-year longitudinal study of a birth cohort
of 1265 children. Measures included assessments of DSM-III-R major depression (at age 14-16); psychiatric disorders, educational
achievement, and social functioning (at age 16-21); social, familial, and
individual factors; and comorbid disorders.
Results Thirteen percent of the cohort developed depression between ages 14
and 16. Young people with depression in adolescence were at significantly
(P<.05) increased risk of later major depression,
anxiety disorders, nicotine dependence, alcohol abuse or dependence, suicide
attempt, educational underachievement, unemployment, and early parenthood.
These associations were similar for girls and boys. The results suggested
the presence of 2 major pathways linking early depression to later outcomes.
First, there was a direct linkage between early depression and increased risk
of later major depression or anxiety disorders. Second, the associations between
early depression and other outcomes were explained by the presence of confounding
social, familial, and individual factors.
Conclusions Young people having early depression were at increased risk of later
adverse psychosocial outcomes. There was a direct linkage in which early depression
was associated with increased risk of later major depression and anxiety disorders.
Linkages between early depression and other outcomes appeared to reflect the
effects of confounding factors.
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